Tumor abnormal protein (TAP) examination contributes to primary diagnosis of bladder cancer.

OBJECTIVE This study aims to investigate the application value of tumor abnormal protein (TAP) examination in the diagnosis of urothelial carcinoma of the bladder. METHOD Abnormal sugar chain glycoproteins in the peripheral blood of 87 patients with urothelial carcinoma of the bladder were detected, and compared with non-tumor patients accompanied by hematuria. RESULT TAP examination showed that the positive rate of the abnormal sugar chain glycoprotein in the peripheral blood of the 87 patients with urothelial carcinoma of the bladder was 78.16%, whereas that of the non-tumor patients was 10.81%. The former is significantly higher than the latter (P<0.01). CONCLUSION TAP examination can be used to detect urothelial carcinoma of the bladder, and would be helpful in the diagnosis of urothelial carcinoma of the bladder by combining the clinical signs and symptoms.